Hormone Health

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WrenLife Hormone Health delivers a research-backed 40:1 inositol ratio, along with key vitamins and minerals that support hormonal, metabolic, and reproductive wellness.*

  • Inositol support: Features myo-inositol and d-chiro inositol in the clinically studied 40:1 ratio to promote hormone balance and metabolic function.*

  • Metabolic health: Includes chromium and magnesium to support healthy insulin sensitivity and blood sugar regulation.*

  • Reproductive wellness: Vitamin D₃ and zinc contribute to normal reproductive function and immune balance.*

  • PCOS-focused lifestyle: Designed to complement nutrition, movement, and other lifestyle habits supportive of hormonal health in women with PCOS.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

 

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    FAQs

    How do inositols support hormone balance and ovarian function?

    In clinical research, myo-inositol and D-chiro-inositol act as second messengers for insulin, helping transport glucose carriers (GLUT-4) to the cell surface. This process supports healthy insulin signaling, which in turn plays a role in maintaining balanced ovarian hormone production.
    When used in a 40:1 ratio, this inositol blend has been shown to support healthy androgen levels and promote regular menstrual cycles as part of a comprehensive wellness routine. *

    These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

    What is inositol-resistant PCOS and how does Hormone Health help?

    Up to one-third of individuals with polycystic ovary syndrome (PCOS) experience what’s referred to as inositol resistance—a reduced ability to absorb or utilize myo‑inositol, possibly related to challenges with intestinal uptake or insulin signaling.

    Hormone Health combines a 40:1 myo-/D‑chiro‑inositol blend with 50 mg of α‑lactalbumin, a milk-derived protein. In clinical studies, α‑lactalbumin significantly improved circulating myo-inositol levels and enhanced the effects of lower inositol doses in participants who had shown limited response to inositol alone.

    By supporting inositol absorption, Hormone Health is designed to help promote healthy insulin signaling and ovarian hormone balance in individuals who may not respond fully to inositols alone.*

    These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

    What results can I expect, and how fast?

    Hormone Health is designed for ongoing, long-term support of hormonal and metabolic balance.

    In clinical studies, daily use of 2 g of myo-inositol combined with a 40:1 blend of supporting nutrients has been associated with improved markers of metabolic health within about four weeks and support for healthy menstrual regularity and ovarian hormone balance by around three months. Preliminary research suggests that adding α‑lactalbumin may enhance inositol absorption and further support normal ovulatory patterns. *

    Individual results may vary, and consistency is key—many users report noticing changes in energy, cycle regularity, and mood within the first 1–3 months of daily use.*

    These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

    Can I take Hormone Health with prescription medications?

    Hormone Health is generally well-tolerated and can often be taken alongside many prescription medications, including hormonal contraceptives. However, because inositols may influence insulin sensitivity, individuals taking medications to manage blood sugar—such as insulin or oral glucose-lowering drugs—should speak with their healthcare provider to ensure appropriate monitoring.

    Those with a milk protein allergy or individuals advised to limit dietary protein should consult their provider before using products containing α-lactalbumin. As with any supplement, share the Supplement Facts panel with your pharmacist or prescriber to help evaluate potential interactions or timing considerations.

    These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

    Can I continue to take Hormone Health during pregnancy?

    Hormone Health is not intended for use during pregnancy. While chromium picolinate is considered safe for non-pregnant adults and those trying to conceive, there is limited research on its safety during pregnancy. Once you become pregnant, we recommend pausing use and speaking with your healthcare provider about switching to a prenatal supplement that contains nutrients like myo-inositol and d-chiro-inositol, which are being studied for their potential role in supporting healthy metabolic function during pregnancy.*

    *Always consult your OB/GYN or healthcare professional before making changes to your supplement routine during pregnancy.
    These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease

    Is Hormone Health safe to take during breastfeeding?

    While most ingredients in this formula are widely used and generally considered safe by breastfeeding women, chromium picolinate lacks sufficient safety data and is not recommended during lactation. Please consult your healthcare provider before using this supplement while breastfeeding

    References

    Bevilacqua, Arturo, and Mariano Bizzarri. “Inositols in Insulin Signaling and Glucose Metabolism.” International Journal of Endocrinology, 2018, Article ID 1968450.

    Bizzarri, Mariano, et al. “Myo‑Inositol and D‑Chiro‑Inositol as Modulators of Ovary Steroidogenesis: A Narrative Review.” Nutrients, vol. 15, no. 8, 2023, article 1875.

    Nordio, Maurizio, et al. “The 40:1 Myo‑Inositol/D‑Chiro‑Inositol Plasma Ratio Is Able to Restore Ovulation in PCOS Patients: Comparison with Other Ratios.” European Review for Medical and Pharmacological Sciences, vol. 23, no. 12, 2019, pp. 5512‑5521.

    Montanino Oliva, Mario, et al. “Effects of *Myo‑*Inositol plus α‑Lactalbumin in *Myo‑*Inositol‑Resistant PCOS Women.” Journal of Ovarian Research, vol. 11, 2018, article 38.

    Hernández Marín, I., et al. “A Multicenter Clinical Study with *Myo‑*Inositol and Alpha‑Lactalbumin in Mexican and Italian PCOS Patients.” European Review for Medical and Pharmacological Sciences, vol. 25, no. 8, 2021, pp. 3316‑3324.

    Kamenov, Zdravko, et al. “Comparing the Efficacy of Myo‑Inositol Plus α‑Lactalbumin vs. Myo‑Inositol Alone on Reproductive and Metabolic Disturbances of Polycystic Ovary Syndrome.” Metabolites, vol. 13, no. 6, 2023, article 717.

    Pustotina, Olga, et al. “The Effects of Myo‑Inositol and D‑Chiro‑Inositol in a Ratio 40:1 on Hormonal and Metabolic Profile in Women with Polycystic Ovary Syndrome.” Gynecological Obstetric Investigation, vol. 89, no. 2, 2024, pp. 131‑139.

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